Author's response to reviews Title:Resolution of the three dimensional structure of components of the glomerular filtration barrier Authors:

Author's response to reviews Title: Creatinine-or cystatin C-based equations to estimate glomerular filtration in the general population: impact on the epidemiology of chronic kidney disease Authors:

Title: Creatinine-or cystatin C-based equations to estimate glomerular filtration in the general population: impact on the epidemiology of chronic kidney disease

Transforming growth factor-beta and the glomerular filtration barrier

The increasing burden of chronic kidney disease worldwide and recent advancements in the understanding of pathologic events leading to kidney injury have opened up new potential avenues for therapies to further diminish progression of kidney disease by targeting the glomerular filtration barrier and reducing proteinuria. The glomerular filtration barrier is affected by many different metabolic ...

Author's response to reviews Title: Implementation of Automated Reporting of Estimated Glomerular Filtration Rate among Veterans Affairs Laboratories: a retrospective study Authors:

Author's response to reviews Title: Characterizing pre-dialysis care in the era of eGFR reporting: a cohort study Authors:

Title: Characterizing pre-dialysis care in the era of eGFR reporting: a cohort study Authors:

New insights into the molecular biology of the glomerular filtration barrier and associated disease.

The glomerular filtration barrier of the kidney can no longer be considered as an inert and adynamic structure, viewed by electron microscopy. Molecular biology, medical genetics and protein chemistry have enabled us to further understand the complex structure and function of this highly specialized barrier of the kidney. Minor aberrations of physiology can lead to fatal disease. Recent advance...